The Journal of the American Medical Association has released a study showing that gonorrhea, the second-most common STD in the United States, is becoming completely drug resistant. There are some strains that are already resistant to every class of antibiotics except for one, the cephalosporins, however, according to an article on ThinkProgress Health, seven percent of patients with resistant strains in Toronto remained infected after being treated with cephalosporins, indicating that this class of drugs is becoming less effective.

The CDC has begun warning doctors away from using cephalosporins as the first round of treatment due to concerns about resistance. There are an estimated 700,000 cases of gonorrhea in the U.S. each year, with perhaps half of those cases getting reported to the CDC.